MovDisordV3, Main, Exploration, bibRecord, 002536

[123I]FP‐CIT SPET imaging in drug‐induced Parkinsonism

Identifieur interne : 002536 ( Main/Exploration ); précédent : 002535; suivant : 002537

[123I]FP‐CIT SPET imaging in drug‐induced Parkinsonism

Auteurs : Michele Tinazzi [Italie] ; Sarah Ottaviani [Italie] ; Ioannis U. Isaias [Italie] ; Isabella Pasquin [Italie] ; Maria Steinmayr [Italie] ; Claudio Vampini [Italie] ; Manuela Pilleri [Italie] ; Giuseppe Moretto [Italie] ; Antonio Fiaschi [Italie] ; Nicola Smania [Italie] ; Piergiorgio Giorgetti [Italie] ; Angelo Antonini [Italie]

Source :

Movement Disorders [ 0885-3185 ] ; 2008-10-15.

RBID : ISTEX:F9BD62C391544AC1CF31F4039642D65D0CF0781D

English descriptors

KwdEn :
- Aged, Aged, 80 and over, Case-Control Studies, Dopamine Antagonists, Dyskinesia, Drug-Induced (radionuclide imaging), Female, Humans, Male, Middle Aged, Parkinson's disease, Parkinsonian Disorders (chemically induced), Parkinsonian Disorders (radionuclide imaging), Statistics, Nonparametric, Tomography, Emission-Computed, Single-Photon (methods), Tropanes (diagnostic use), Young Adult, [123I]FP‐CIT SPET, dopamine transporter, drug‐induced parkinsonism.
MESH :
- chemical , diagnostic use : Tropanes.
- chemical : Dopamine Antagonists.
- chemically induced : Parkinsonian Disorders.
- methods : Tomography, Emission-Computed, Single-Photon.
- radionuclide imaging : Dyskinesia, Drug-Induced, Parkinsonian Disorders.
- Aged, Aged, 80 and over, Case-Control Studies, Female, Humans, Male, Middle Aged, Statistics, Nonparametric, Young Adult.

Abstract

We assessed the status of dopamine nerve terminals in patients treated with dopamine receptor blocking agents (DRBAs) who had developed drug‐induced parkinsonism (DIP). We performed [123I]FP‐CIT SPET in 32 consecutive patients who were on DRBAs for at least 6 months and developed extrapyramidal signs. The UPDRS‐III was used to assess clinical severity. Twenty‐six age‐ and sex‐matched healthy subjects served as control group. Putamen [123I]FP‐CIT SPET binding was reduced in 14 and normal in the remaining 18 patients. There was no difference between the two groups for age, duration of DRBAs treatment, UPDRS III, tremor, rigidity, and bradykinesia subscores for upper and lower limbs. Conversely, symmetry of parkinsonian signs and presence bucco‐linguo‐masticatory dyskinesias were more frequent in individuals with normal tracer binding. Imaging of the dopamine transporter may help to identify subjects with DIP secondary to a loss of dopamine nerve terminals. © 2008 Movement Disorder Society

Url:

https://api.istex.fr/document/F9BD62C391544AC1CF31F4039642D65D0CF0781D/fulltext/pdf

DOI: 10.1002/mds.22098

Affiliations:

Italie

Le document en format XML

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<author><name sortKey="Tinazzi, Michele" sort="Tinazzi, Michele" uniqKey="Tinazzi M" first="Michele" last="Tinazzi">Michele Tinazzi</name>
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<author><name sortKey="Ottaviani, Sarah" sort="Ottaviani, Sarah" uniqKey="Ottaviani S" first="Sarah" last="Ottaviani">Sarah Ottaviani</name>
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<author><name sortKey="Isaias, Ioannis U" sort="Isaias, Ioannis U" uniqKey="Isaias I" first="Ioannis U." last="Isaias">Ioannis U. Isaias</name>
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<author><name sortKey="Pasquin, Isabella" sort="Pasquin, Isabella" uniqKey="Pasquin I" first="Isabella" last="Pasquin">Isabella Pasquin</name>
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<author><name sortKey="Steinmayr, Maria" sort="Steinmayr, Maria" uniqKey="Steinmayr M" first="Maria" last="Steinmayr">Maria Steinmayr</name>
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<author><name sortKey="Vampini, Claudio" sort="Vampini, Claudio" uniqKey="Vampini C" first="Claudio" last="Vampini">Claudio Vampini</name>
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<author><name sortKey="Pilleri, Manuela" sort="Pilleri, Manuela" uniqKey="Pilleri M" first="Manuela" last="Pilleri">Manuela Pilleri</name>
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<author><name sortKey="Moretto, Giuseppe" sort="Moretto, Giuseppe" uniqKey="Moretto G" first="Giuseppe" last="Moretto">Giuseppe Moretto</name>
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<author><name sortKey="Fiaschi, Antonio" sort="Fiaschi, Antonio" uniqKey="Fiaschi A" first="Antonio" last="Fiaschi">Antonio Fiaschi</name>
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<author><name sortKey="Smania, Nicola" sort="Smania, Nicola" uniqKey="Smania N" first="Nicola" last="Smania">Nicola Smania</name>
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<author><name sortKey="Giorgetti, Piergiorgio" sort="Giorgetti, Piergiorgio" uniqKey="Giorgetti P" first="Piergiorgio" last="Giorgetti">Piergiorgio Giorgetti</name>
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<author><name sortKey="Smania, Nicola" sort="Smania, Nicola" uniqKey="Smania N" first="Nicola" last="Smania">Nicola Smania</name>
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<author><name sortKey="Giorgetti, Piergiorgio" sort="Giorgetti, Piergiorgio" uniqKey="Giorgetti P" first="Piergiorgio" last="Giorgetti">Piergiorgio Giorgetti</name>
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<author><name sortKey="Antonini, Angelo" sort="Antonini, Angelo" uniqKey="Antonini A" first="Angelo" last="Antonini">Angelo Antonini</name>
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<series><title level="j">Movement Disorders</title>
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<term>Aged, 80 and over</term>
<term>Case-Control Studies</term>
<term>Dopamine Antagonists</term>
<term>Dyskinesia, Drug-Induced (radionuclide imaging)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson's disease</term>
<term>Parkinsonian Disorders (chemically induced)</term>
<term>Parkinsonian Disorders (radionuclide imaging)</term>
<term>Statistics, Nonparametric</term>
<term>Tomography, Emission-Computed, Single-Photon (methods)</term>
<term>Tropanes (diagnostic use)</term>
<term>Young Adult</term>
<term>[123I]FP‐CIT SPET</term>
<term>dopamine transporter</term>
<term>drug‐induced parkinsonism</term>
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<front><div type="abstract" xml:lang="en">We assessed the status of dopamine nerve terminals in patients treated with dopamine receptor blocking agents (DRBAs) who had developed drug‐induced parkinsonism (DIP). We performed [123I]FP‐CIT SPET in 32 consecutive patients who were on DRBAs for at least 6 months and developed extrapyramidal signs. The UPDRS‐III was used to assess clinical severity. Twenty‐six age‐ and sex‐matched healthy subjects served as control group. Putamen [123I]FP‐CIT SPET binding was reduced in 14 and normal in the remaining 18 patients. There was no difference between the two groups for age, duration of DRBAs treatment, UPDRS III, tremor, rigidity, and bradykinesia subscores for upper and lower limbs. Conversely, symmetry of parkinsonian signs and presence bucco‐linguo‐masticatory dyskinesias were more frequent in individuals with normal tracer binding. Imaging of the dopamine transporter may help to identify subjects with DIP secondary to a loss of dopamine nerve terminals. © 2008 Movement Disorder Society</div>
</front>
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<tree><country name="Italie"><noRegion><name sortKey="Tinazzi, Michele" sort="Tinazzi, Michele" uniqKey="Tinazzi M" first="Michele" last="Tinazzi">Michele Tinazzi</name>
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<name sortKey="Antonini, Angelo" sort="Antonini, Angelo" uniqKey="Antonini A" first="Angelo" last="Antonini">Angelo Antonini</name>
<name sortKey="Fiaschi, Antonio" sort="Fiaschi, Antonio" uniqKey="Fiaschi A" first="Antonio" last="Fiaschi">Antonio Fiaschi</name>
<name sortKey="Giorgetti, Piergiorgio" sort="Giorgetti, Piergiorgio" uniqKey="Giorgetti P" first="Piergiorgio" last="Giorgetti">Piergiorgio Giorgetti</name>
<name sortKey="Isaias, Ioannis U" sort="Isaias, Ioannis U" uniqKey="Isaias I" first="Ioannis U." last="Isaias">Ioannis U. Isaias</name>
<name sortKey="Moretto, Giuseppe" sort="Moretto, Giuseppe" uniqKey="Moretto G" first="Giuseppe" last="Moretto">Giuseppe Moretto</name>
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<name sortKey="Pilleri, Manuela" sort="Pilleri, Manuela" uniqKey="Pilleri M" first="Manuela" last="Pilleri">Manuela Pilleri</name>
<name sortKey="Smania, Nicola" sort="Smania, Nicola" uniqKey="Smania N" first="Nicola" last="Smania">Nicola Smania</name>
<name sortKey="Steinmayr, Maria" sort="Steinmayr, Maria" uniqKey="Steinmayr M" first="Maria" last="Steinmayr">Maria Steinmayr</name>
<name sortKey="Tinazzi, Michele" sort="Tinazzi, Michele" uniqKey="Tinazzi M" first="Michele" last="Tinazzi">Michele Tinazzi</name>
<name sortKey="Vampini, Claudio" sort="Vampini, Claudio" uniqKey="Vampini C" first="Claudio" last="Vampini">Claudio Vampini</name>
</country>
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Movement Disorders (revue)

[123I]FP‐CIT SPET imaging in drug‐induced Parkinsonism

[123I]FP‐CIT SPET imaging in drug‐induced Parkinsonism

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

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	Movement Disorders (revue)
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